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Strength points and limitations Based on our knowledge, this is the most updated meta-analysis on this topic, including all available evidence based on our inclusion criteria of including only controlled studies, either RCTs or controlled observational studies, to reach the highest accessible quality of evidence from the available evidence found in the literature

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Lancet Oncol (2020) 21(9):11346

[7] Niacin can cause vasodilation, so it should be avoided in those with serious hypotension

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