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After incubation, the protein solution was analysed by gel filtration chromatography on a HiLoad 16/60 Superdex 200 prep grade column (GE Healthcare), which was connected to an KTAFPLC system (GE Healthcare)

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents

AOD-9604 isolates only the fat-tissue effects without the broader hormonal cascade

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In response to various stimuli, I B undergoes proteolytic degradation, which allows nuclear translocation of NF- B leading to gene activation (Baeuerle and Baltimore, 1988 #733)