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Moreover, inhibition of heat shock factor-1 (HSF-1) dependent heat shock protein beta 1 (HSPB1) expression can also inhibit erastin-induced ferroptosis (Sun et al., 2015)

Nevertheless, a significant dissimilarity of beta diversity on fecal microbiota was observed between healthy control and cirrhotic patients regardless of MDRO carriage ( p =0.001), as well as between cirrhotic patients with and without MDRO carriage ( p =0.033)

It is known that BAs may regulate multiple physiological and pathological processes, implicating a role in the progression of NAFLD/NASH ( Bacteroides and Clostridium , which produced DCA accumulation in the feces, serum, and liver, and hepatic DCA led to sucralose-induced NAFLD in mice ( Accumulating studies have demonstrated that amino acids might play a role in the process of NAFLD/NASH, but the relationship hasnt been elucidated

In cancer, CDO has been shown to divert the flow of cysteine away from glutathione synthesis, thereby promoting the production of ROS

10.1007/s11064-012-0775-4 38