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The beneficial in vivo antioxidant effects of all these antioxidants, except vitamin E, remain limited, as documented by various clinical trials (Halliwell 2022)

212 In patients with headache ( n = 31), including migraine and other types of chronic headache, 5-HTP (400 mg daily) for 2 months showed that 48% of participants had a greater than 50% average reduction in headache symptoms

The intestinal barrier and its dysfunction in patients with metabolic diseases and non-alcoholic fatty liver disease

However, some people may experience the following side effects from taking creatine: nausea stomach pain diarrhea muscle cramping In higher dosages over long periods of time, supplementation with creatine may affect the liver or kidneys