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Study Drug and Procedures Participants were required to remain at the study site from the evening of Day 1 until the morning of Day 7

The use of methotrexate may additionally invalidate diagnostic assays for folic acid and vitamin B12

Rabe E, Stucker M, Esperester A, Schafer E, Ottillinger B

However, as Moncrieff and colleagues point out in an attractive systemic review, there is no convincing evidence that depression could be associated with or caused by lower serotonin concentrations or activity [94]

Write the reconstitution date on the vial using a permanent marker so you can track when the medication expires