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Primary human T cells Primary human T cells were obtained from anonymous donors through the Human Immunology Core at the University of Pennsylvania (Philadelphia, Pennsylvania) under a protocol approved by the Childrens Hospital of Philadelphia Institutional Review Board

doi: 10.1104/pp.110.171918

10.1038/nrneurol.2015.228 18 KorjaM.LehtoH.JuvelaS

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Furthermore, similar to the tau protein, A can form stable dityrosine cross-linked dimers with DIY under oxidative stress conditions, which exacerbates the detrimental effects of oxidative stress on neuronal cells (Smith et al., 2007)