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For caries prevention specifically, we rely on surrogate markers (plaque reduction, S

RH: Conceptualization, Funding acquisition, Project administration, Supervision, Writing review & editing

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The Serum Timing Map Here is the idea this whole guide turns on

Hydroxyl radicals are extremely reactive, cannot be scavenged by enzymatic reaction, and have a diffusion controlled half-life of ~10 9 s before reacting with organic molecules in vivo (Freinbichler et al., 2011), suggesting that hydroxyl radical damage would occur in close spatial proximity to copper ions