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Elevated activity of YAP/TAZ is particularly noteworthy in various squamous carcinomas, as they are among the malignancies bearing the highest amplification frequency of these factors, which include cervical, lung, head and neck, bladder, and esophageal squamous cell carcinomas (SCCs) [25]

The hypomethylation-associated upregulation of PLCE1 has been linked to tumorigenesis, tumor angiogenesis and poor prognosis in ESCC [113]

Most traditionally trained doctors focus on treating individual symptoms rather than searching for a systemic, environmental cause

doi: 10.1016/j.drugalcdep.2005.05.013 22 CohenJCollinsRDarkesJGwartneyD

Participants engage in group therapy sessions that foster a sense of community and shared experiences