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For example, to treat or ameliorate the effects of epilepsy, a subject may be administered an effective amount of one or more compounds or pharmaceutical compositions of the present invention and, e.g., one or more of the following: Albendazole, Banzel, BGG492 (Novartis Corp., New York, N.Y.) Carbamazepine, Carbatrol, Clobazam, Clonazepam, Depakene, Depakote, Depakote ER, Diastat, Diazepam, Dilantin, Eslicarbazepine acetate, Ethosuximide, Ezogabine, Felbatol, Felbamate, Frisium, Gabapentin, Gabitril, Inovelon, JNJ-26489112 (Johnson and Johnson, New Brunswick, N.J.) Keppra, Keppra XR, Klonopin, Lacosamide, Lamictal, Lamotrigine, Levetiracetam, Lorazepam, Luminal, Lyrica, Mysoline, Memantine, Neurontin, Onfi, Oxcarbazepine, Phenobarbital, Phenytek, Phenytoin, Potiga, Primidone, probenecid, PRX-00023 (EPIX Pharmaceuticals Inc, Lexington, Mass.), Rufinamide, Sabril, Tegretol, Tegretol XR, Tiagabine, Topamax, Topiramate, Trileptal, Valproic Acid, Vimpat, Zarontin, Zonegran, and Zonisamide

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This is the first time that toxic Al was not observed in the surface cells, although the mechanism and reason for such a distribution remains to be clarified