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To further improve targeting and reduce cytotoxicity, Kesharwani et al

Interestingly, optimized deliveries of spermidine and other (poly)amines could potentially be achieved through the use of advanced nanomaterials acting as smart carriers 72 , such as with efforts to deliver spermidine using silica-based nanoporous pods as an anticancer agent 73 , and with examples of agro-based approaches including the smart delivery of putrescine using carbon quantum dots against salt stress 74 and heavy metal stress 75 in grapevine plants