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RAS-selective lethal 3 (RSL3) inhibits GPX4 by covalently binding to it, leading to lipid peroxide accumulation and ferroptosis induction

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25 Nevertheless, it is important to note that the atherosclerotic process often begins in childhood, particularly in children with overweight and obesity and those with high blood glucose levels

when the tumor progresses to the advanced stage, ROS exceeds the critical value, promoting DNA double-strand breaks and the 8-oxodG formation and leading to apoptosis

L-Carnitine - Fat Metabolism: L-Carnitine plays a crucial role in transporting fatty acids into the mitochondria, where they are burned for energy