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Description

These reactive molecules can interact with various cellular components, leading to cellular damage and various pathological changes

Its human nature

As with CYP2E1, there are substantial inter-ethnic differences in CYP2D6 across populations, ranging from complete loss of function or reduction in functional activity (2570% of the population, dependent on ethnic origin and geographical location) to extensive, ultra-rapid metabolisers (1.59.3% of the population) (see Table 3 in the supplementary data for a summary of the evidence) [17, 38]

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LuLYangLKYueJWangXSQiJYYangFet alScutellarin alleviates depression-like behaviors induced by LPS in mice partially through inhibition of astrocyte-mediated neuroinflammation