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7 , e1016 (2018)

10.1038/nature12820 20

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Dosing Protocol Suggested daily titration approach based on clinical trial protocols [4] [5]

Additionally, hyperglycemia can lead to histological alterations in the epididymal duct, including decreased germ cell populations, reduced stereocilia, clustering of epithelial cells, lipid vacuolization, and inflammation ( Reduced sperm quality is a recognized issue in diabetes, particularly in cases of T1DM