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The 4-HNE-induced ERK1/2 activation was mediated by repressing mitogen-activated protein kinase phosphatase-1 (MKP-1), a negative regulator of ERK1/2, through a proteasome-dependent degradation mechanism

527 In lupus-prone mice, CQ promotes the expansion of Treg populations and suppresses CNS inflammation under both prophylactic and therapeutic dosing regimens

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Phenolic chemicals contained in these mushrooms (such as gallic acid, ferulic acid, and caffeic acid) have an important role in carcinogenesis prevention by reducing free radical formation and altering signaling pathways involved in cell proliferation and death

Liu N, Xiong Y, Ren Y, Zhang L, He X, Wang X, et al