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These lines of research suggest that sEHIs may have potential therapeutic effect in managing AD associated memory impairment

More broadly, the need for careful safety monitoring is also underscored by experience with anti-amyloid therapies, in which ARIA the risk of amyloid-related imaging abnormalities (ARIA) has been associated with drug dose, APOE 4 status, baseline microhemorrhages, and other vascular risk factors (Doran and Sawyer, 2024)

To explore possible roles of D1/D5 receptors in endothelial dysfunctions in the setting of TTC, the production of NO was measured in HCMECs treated with epinephrine and D1/D5 agonists SKF38393 or fenoldopam