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Banner, A., and M

IDH3 is the primary form of IDH in the TCA cycle, whose function is to convert isocitrate to -KG

A related study found that supplementing with 600 mg of alpha-lipoic acid for 10 days prior to noise exposure suggested some protection against changes in hearing measures compared to baseline, but the absence of a placebo group makes the results unreliable [26]

The proposed mechanisms of keto-induction are typically extrapolated forwards from known physiological changes in fasting and carbohydrate withdrawal, and backwards from the observed symptoms in trials of KD initiation