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These results support that MeCbl specifically targets GSDME but not upstream caspase or other GSDMs

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CTRP13 preserves endothelial function by targeting GTP cyclohydrolase 1 in diabetes

The primary antibodies utilized in this study included IL-1 (1:50 dilution, 52012, Santa Cruz Biotechnology, America), TNF- (1:50 dilution, 346654, ZEN-BIOSCIENCE, China), CD44 (1:100 dilution, 14044182, eBioscience, America), ALP (1:50 dilution, 381009, ZEN-BIOSCIENCE, China), and BMP2/4 (1:50 dilution, 137087, Santa Cruz Biotechnology, America)