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A case series (GSH soap: 15 patients) reported skin lightening based on photography

ERS activates a series of cascading reaction pathways, regulating the formation of intracellular iron ions and ROS through iron metabolism, Xc-/GPX4 system (Zhao et al., 2021), lipid metabolism (Tak et al., 2022), and other ferroptosis pathways such as p62-Keap1-NRF2, p53-SAT1-ALOX15, ATG5-ATG7-NCOA4, and glutaminolysis (Lane et al., 2018), playing a dual role in ferroptosis

GSH metabolism contributes to FA tolerance in DNA-repair deficient cells Finally, we reasoned that the reaction between FA and GSH forming HSMGSH molecules and their metabolization by ADH5 might limit free FA

They work by mimicking the natural hormone GLP-1, which plays a role in regulating appetite and digestion