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The absence of muscle-building effects means weight changes reflect primarily fat loss rather than mixed body recomposition

Federation, (International Diabetes Federation, Brussels, 2019)

10.1038/nbt.3955 [DOI] [PMC free article] [PubMed] [Google Scholar] Lin HK, Hu YC, Yang L, Altuwaijri S, Chen YT, Kang HY, Chang C (2003) Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers

Conversely, evidence suggests that the use of sulfonylureas and thiazolidinediones may be associated with impaired sperm quality, exerting detrimental effects on motility and vitality (67)