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However, high dose oral vitamin B12 therapy can also be effective, provided that the dose is sufficient, medication adherence is good, and a response is documented

A Specified Substance or Method is that which potentially allows, under defined conditions, for a greater reduction of a sanction when an athlete tests positive for that particular substance

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Mutation, deletion or inactivation of the gene that encodes ALS in humans and mice decreases circulating levels of IGF-1 and IGFBP-3, causing moderate growth deficiency and abnormalities in bone and carbohydrate metabolism