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Seydi Ykm, [email protected]

The median MELD score at LT was 30 [IQR 22-35]

For example, RSL3 inhibits the activity of GPX4 by covalently binding to its Sec residue (171), while Erastin blocks System Xc, further exacerbating GSH depletion

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This adipose dysfunction increases lipid flux to peripheral organs, particularly through portal circulation to the liver, accelerating broader metabolic disease progression (400)