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discovered that mitoROS directly regulate cyclin-dependent kinase 2 (CDK2), targeting a specific conserved cysteine and disrupting the regulatory CDK-related phosphatase (KAP), thus influencing the cell cycle ( Moreover, mitochondria regulate intracellular calcium levels, and their strategic localization within the cell helps compartmentalize calcium signals

Semaglutide is an FDA-approved peptide drug used to manage type 2 diabetes and obesity