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The treatment should be administered slowly to tolerance to minimize potential side effects

These synthetic type smooth muscle cells, characterized by their high expression of -smooth muscle actin, suggest that this marker may be valuable for diagnosing IC/PBS (Lutgendorf et al., 2002)

As mentioned above, -syn can interfere with translocation of mitochondrial-target proteins, thereby disrupting the proper functioning of the ETC, and leading to elevated levels of intracellular oxidative stress (Di Maio et al., 2016)