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These striae albae are avascular blood vessels have retreated and fibroblast activity has largely ceased

93 In IPF, abnormally activated Wnt signalling is detected, which manifests as follows: significantly increased expression of Wnt1, Wnt7b, Wnt10b, FZD2, FZD3, -catenin, and LEF1 in the lung tissue, thereby promoting fibroblast proliferation and epithelial cell-mesenchymal transition, the pathological process of IPF

RMT involves internalization of receptor-ligand complexes at the luminal surface of endothelial cells, vesicular trafficking, and release at the abluminal side

Are symptoms stable, improving, or worsening

Topical and intraperitoneal TB4 increased re-epithelialisation by 42% over saline controls at day 4, and by up to 61% at day 7 post-wounding