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This convergence contributes to reduced physiological reserve, increased vulnerability to stressors, and ultimately, shortened lifespan [48]

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10.1093/ajcn/84.3.587 10 BairdD

CAP acts on the large ribosomal subunit (LSU) by inhibition of peptide bond formation, thereby stalling mitoribosomes resulting in loss of mitochondrial translation with subsequent loss of mitochondrial-encoded respiratory chain complexes (Figs

Typically, weekly sessions are held initially, followed by bi-weekly or monthly maintenance sessions