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Description

Among the 226 patients who received cisplatin with pemetrexed, 74% received full supplementation with folic acid and vitamin B 12 during study therapy, 14% were never supplemented, and 12% were partially supplemented

Epub 2013 May 9

Because folate status is a major determinant of blood homocysteine concentrations, the possible contribution of elevated homocysteine to the pathogenesis of NTDs has been postulated