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Description

doi: 10.3945/an.116.013177

By using biocompatible lipids, liposomes protect the glutathione and allow it to be transported through the lymphatic system, which also avoids the first-pass hepatic metabolism of the glutathione

The supernatant was collected after centrifugation and protein content was determined

Our study is first to demonstrate novel molecular mechanisms involved in the sensitization of PTC cells to ferroptosis inducer- we show that RSL3, a potent direct GPX4 inhibitor, effectively reduces the viability of thyroid cancer lines with various mutational backgrounds compared to HThF control cell line in a dose-dependent manner