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If the patient has an autoimmune disease or another condition that prevents the stomach from making intrinsic factor, then Vitamin B12 injections may be a better option

Welsh JP, Lang EJ, Suglhara I, Llins R

The low incidences of vitamin B12 deficiency and the reduced need for replacement after PG-DTR in this study align with the results of the KLASS-05 randomized controlled trial (RCT) and meta-analysis [3,5]

Cobalamin (vitamin B 12 ) Deficiency Investigation & Management Early treatment of cobalamin deficiency is particularly important because neurologic symptoms may be irreversible