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This interaction diminishes the antioxidative defenses of cells, leading to an increase in lipid ROS, and thereby initiating ferroptosis [7, 9, 10]

At the level of Peyer's patches, SIgA can mediate antigens selective translocation, first binding them and then promoting their apical-to-basal transepithelial migration via M cells, dendritic cells, and T cells (153156)