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(2013) demonstrated abnormal binding of HbS to the RBC membrane in SCD, resulting in an impaired ability of SCD RBCs to sequester the glycolytic EMP enzymes

Interestingly, 5-fluorouracil treatment shows little effect on the Ki-67-positive cells but remarkably inhibits doublecortin (DCX)-positive cell number, indicating that early neuronal neogenesis is affected (Mustafa et al., 2008)

doi: 10.1016/S0016-7037(02)01279-6

If you suspect it is causing a B12 deficiency your doctor will be able to test for this, but will also recommend you cut down on or stop drinking alcohol in order to benefit from B12 injections, if this is the recommended treatment, he says

doi:10.3109/10409238.2013.764840 Navarro-Yepes J, Burns M, Anandhan A, Khalimonchuk O, Del Razo LM, Quintanilla-Vega B, Pappa A, Panayiotidis MI, Franco R (2014) Oxidative stress, redox signaling, and autophagy: cell death versus survival