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It is important to note that mitochondrial composition in tumors is highly heterogeneous, and both metabolic demands and genetic backgrounds differ markedly from those observed in inherited mitochondrial disorders

2.4 The ferroptosis-inflammation vicious cycle drives chronic periodontitis Growing evidence indicates that ferroptosis can trigger inflammatory responses, while the inflammatory microenvironment further promotes ferroptosis, forming a self-amplifying vicious cycle that drives the persistent progression of chronic periodontitis

Long noncoding RNA URB1-antisense RNA 1 (AS1) suppresses sorafenib-induced ferroptosis in hepatocellular carcinoma by driving ferritin phase separation

MYB-RELATED TRANSCRIPTION FACTOR A transcription factor that contains a DNA-binding domain that shows sequence similarity to vMYB, the first-described member of this family

It neutralizes reactive oxygen species (free radicals) and helps protect cells from oxidative stress, which can damage DNA, proteins, and cellular membranes