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The concentrations of caspase-3, caspase-6, caspase-7, caspase-8, and caspase-9 were significantly higher in MCF-7 and MDA-MB-231 cell lines treated with abemaciclib and IRR (10 Gy), compared to abemaciclib-treated cells (Fig

Intracellular superoxide and hydrogen peroxide concentrations: a critical balance that determines survival or death

CD147, on the other hand, activates the FAK-Scr pathway, leading to tyrosine phosphorylation of IP3R1, which enhances the affinity of the receptor for IP3 (Jayaraman et al., 1996

In addition, ferritinophagy also participates in the regulation of intracellular iron levels, that is, it sends ferritin to lysosomes for degradation (Mancias et al., 2014)

After exposure, the tissues were placed back into their multi-well culture plates containing the same medium, a further aliquot of media was added apically (20 L for Akemi, 75 L for all others except LPS) and returned to incubator until next exposure