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However, beyond these two measurement issues (and the short list of potential confounds mentioned above), a large cytokine methods literature demonstrates a staggering number of potential confounds in the measure of cytokines, with potential problems arising at every step of the way

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doi: 10.1016/j.dnarep.2006.07.001 58 ColicchioR.RicciS.LambertiF.PagliaruloC.PagliucaC.BraioneV.et al

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Conclusion: Hence the subclinical hypothyroidism, prevalent in overweight individuals aged 46-60 particularly in female is very high compare to overt hypothyroidism, where TSH was positively correlated with the Glutathione peroxidase (GPx) and Malondialdehyde (MDA), representing increased TSH levels are associated with increased oxidative stress in body