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367 Another NQO1 substrate, ARQ501, was shown to cause stable disease in a phase 1 trial, 368 and DNQ is 10-fold more potent than -lapachone

Cell Death Dis (2017) 8(5):e2757

[77], dogs with symptoms of diabetes mellitus were fed an oral turmeric extract capsule containing 250 mg of curcuminoids for 180 days

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Omi/high-temperature requirement serine protease A2 (HtrA2), a proapoptotic serine protease mainly found in and released from mitochondria, is found to be involved in the development of BBB dysfunction and SAE induced by sepsis through a caspase-dependent mitochondrial pathway (Wang et al., 2018