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While translational gaps persist, particularly in dosing, timing, and patient stratification, emerging strategies including mitochondria-targeted antioxidants, nanotherapeutics, and biomarker-guided interventions hold promise for restoring redox homeostasis and improving clinical outcomes

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The generation of highly reactive ROS is an important feature of the normal cellular system such as fertilization, ovulation, arachidonic acid metabolism, phagocytosis, and mitochondrial respiratory chain

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[DOI] [PubMed] [Google Scholar] 52.Anachad O., Taouil A., Taha W., Bennis F., Chegdani F