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Disturbances in GHS balance have been implicated in the progression of a number of diseases like cancer, cystic fibrosis, and neurodegenerative, cardiovascular, inflammatory, immune, and metabolic diseases

10.1016/S0887-8994(97)00026-X Warter JM, Imler M, Marescaux C, Chabrier G, Rumbach L, Micheletti G, Krieger J: Sodium valproate-induced hyperammonemia in the rat: role of the kidney

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Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method

The compromised oral bioavailability and excessive cytotoxic effects of 5AC and decitabine created increased demand for developing new nucleoside analogs such as 6-thioguanine (6-TG), zebularine and guadecitabine (SGI-110)