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Together, these findings suggest that peripheral biomarkers have the potential to become a valuable diagnostic aid across multiple forms of dementia, offering a rare blend of accessibility, biomarker specificity, and emerging commercial viability

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4.5 Acetylcholinesterase activity (AChE) Patients with concurrent symptoms of reduced salivation and dry mouth have been observed as a consequence of employing AChE as a diagnostic biomarker for PD

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Nuclear sphingolipid metabolism

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226 PPAR agonists, such as the thiazolidinediones, rosiglitazone and pioglitazone, have been shown to reduce lung inflammation in mouse models of tobacco smoke, and studies have found that treating model mice with thiazolidinedione can reverse emphysema

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