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It is well established that in order to be effective in treating solid tumor cancers, the current treatment methods used often sacrifice surrounding healthy tissue and cause damage at the site of treatment, inducing changes to the surrounding microenvironment

Supplementary information Glossary Active comparators Treatment or intervention used as a comparison group in a clinical trial, which is known to be effective for the condition being studied or is already used as a standard treatment

10.1038/s41598-017-01271-9 236 ZakhariS

Lower levels of C-reactive protein (CRP), leptin, and adiponectin were observed in a study by Varady et al

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