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Melanotan II (Tan Jabs): Why They're Not Worth The Risk Targeting the Brain to Protect the Heart PMC Melanotan II, also known as 'The Barbie Drug,' is an unregulated substance with serious reported side effects that is not safe for consumer use. The bottom line: Melanotan II has The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system ScienceDirect Your body already makes a hormone that tells your skin to tan. Melanotan 2 is a synthetic peptide engineered to mimic that hormone but in a version that's more potent and longer lasting than
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