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These side-reactions posed severe challenges to data reliability and further impeded the in-depth investigation of thiol metabolism

However, mechanistic insight into the interactions among sweeteners, xenobiotics, and gut bacteria remains limited, highlighting the need for accessible in vitro approaches to complement correlative analyses of fecal microbial communities and in vivo models

These findings further support how understanding ROS dynamics between mitochondrial microdomains can reveal how ROS can act as a metabolic signal which propagates within the mitochondrial network, influencing cell-wide physiological responses over short timescales

Also, we would like to thank National NeuroAIDS Tissue Consortium (NNTC) for providing all human samples