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The authors investigated the glutathione (GSH) levels, which are the indicators of ROS, and they found that significant differences were found in the treatment group and PTZ controlled group

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The activation of the JAK/STAT signalling cascade by IFN- drives microglia toward a proinflammatory M1 state, thereby accelerating neuronal damage, particularly in inflammatory environments enriched with cytokines such as TNF- and IL-1 [186, 198]

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