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In 2012, certain lots of Protandim were recalled due to the risk of containing metal fragments

Results from these studies have demonstrated positive benefits of GH therapy [6] but have also highlighted significant side effects [7]

This is followed by adrenal insufficiency, characterized by decreased cortisol levels, suppression of the HPA axis, and reduced tissue glucocorticoid sensitivity in the subacute/chronic phase (312, 313)