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Description

We demonstrated increased levels of the glutamate N-methyl-D-aspartate receptor (NMDAR) co-agonist D-serine and its precursor L-serine in the (1) rostral putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated monkeys 3 , (2) post-mortem striatum of human PD brains, and (3) CSF of de novo PD patients compared to patients with other neurodegenerative diseases and controls 4

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In 1996, encephalopathy triggered by GFAP autoantibodies (GFAP-A) was described 258

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Furthermore, compared with PROTACs, molecular glues lack linkers, rendering them favorable drug-like properties, including lower molecular weights, fewer hydrogen bond donors, and fewer rotatable bonds

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Similarly, microneedlinga procedure that creates tiny injuries in the skin to stimulate collagen productionhas also been shown to be a safe and effective way to treat melasma

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