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doi: 10.1016/S0070-2137(01)80004-2 30 Martinez-ChantarM

Mol Cell Endocrinol 458:615

Higher Lp(a) levels were also linked to increased presence of low-density plaques and greater inflammatory signaling in fat tissue surrounding the heart

EFFECTS ON EXPERIMENTAL ANIMALS AND IN VITRO TEST SYSTEMS 8.1 Single exposure 8.1.1 LD 50 and LC 50 values 8.2 Short-term exposure 8.2.1 Oral 8.2.2 Inhalation 8.2.3 Dermal 8.2.4 Parenteral 8.3 Skin and eye irritation

The reliance of MDSCs on glucose and glycolytic metabolism has been extensively targeted, either by depleting glucose (e.g., 2-DG) or inhibiting glucose transporters and glycolytic enzymes such as GLUT3 or pyruvate dehydrogenases (e.g., DCA) (31, 32)