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Eur Hear J Cardiovasc Pharmacother 3:108117 Brouwers FP, de Boer RA, van der Harst P et al (2013) Incidence and epidemiology of new onset heart failure with preserved vs
PMID: 20922415
Early engagement with healthcare services, combined with evidence-based lifestyle modifications (weight loss, dietary improvement, increased physical activity), offers the best opportunity for disease reversal or stabilisation and reduces the risk of progression to cirrhosis or liver failure
adjusted HR 1.09, 95% CI 1.031.16, p for trend = 0.010, p = 0.005, variation independent of the mean
These interventions have increased DOX accumulation and enhanced its antitumor activity in drug-resistant cancer cell lines (e.g., A2780/DX, LoVo/DX) [116,117,118,119,120,121,122,123]
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