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Cornus officinalis methanol extract upregulates melanogenesis in Melan-a cells

Enzymes such as Acyl-CoA synthetase long-chain family member 4 and lysophosphatidylcholine acyltransferase 3 (ACSL4 and LPCAT3) promote PUFA incorporation into phospholipids, thereby increasing ferroptotic vulnerability [54, 55]