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Dehydration worsens headaches, constipation, and fatigue, all of which are common complaints during weight loss protocols

Low B12 causes weakness, fatigue, and depression, but also other symptoms, including numbness or tingling in the hands, feet, and legs

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Gastritis, celiac disease, and inflammatory bowel disease (IBD) may lead to a deficiency because these conditions reduce nutrient absorption

5-Amino-1MQ is a small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor studied in relation to NAD+ salvage pathway regulation and adipocyte metabolism