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Injection site reactions affect roughly 3.2% of tirzepatide users in clinical trials, compared to just 0.4% on placebo

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We then compared the production of thiomethyl metabolites after exposure to APAP, and 3 of its potential direct precursors: the glutathione conjugate (APAP-SG), APAP-Cys, and NAC-APAP for 24h in HRG cells and PHH (Fig