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In diabetic retinopathy, the treatment can be administered every eight to 12 weeks thereafter, while the dosing interval can stretch up to 16 weeks in patients with wet age-related macular degenerationand diabetic macular edema

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The reason for the difference between reported cases and estimated actual cases of Lyme disease is that there are many requirements for reporting, which, in some states, require the medical provider to interact with the states Department of Health