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10.1113/jphysiol.2010.198564 42 HoriT.TakahashiT

Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

Therefore, nano-based formulations of silibinin demonstrate significant improvements in drug bioavailability, stability, and apoptotic efficacy across various cancer models, highlighting their potential as cutting-edge therapeutic alternatives